Acrasin

An acrasin is a pheromone used by species of slime mold,[1] which signals to the many individual cells and triggers an aggregation response, such that they form a single large cell (a plasmodium). One of the earliest acrasins to be identified was cyclic AMP, found in the species Dictyostelium discoideum by Brian Shaffer,[2] which exhibits a complex swirling-pulsating spiral pattern when forming a pseudoplasmodium.[3]

The term "acrasin" is a reference to the character Acrasia in Edmund Spenser's Faerie Queene,[4] who seduced men against their will and then transformed them into beasts. Acrasia is itself a play on the Greek akrasia that describes loss of free will.

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