ABI2

ABI2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2ED0, 3P8C, 4N78
Identifiers
Aliases	ABI2, ABI-2, ABI2B, AIP-1, AblBP3, SSH3BP2, argBP1, argBPIA, argBPIB, abl-interactor 2, abl interactor 2, AIP1
External IDs	OMIM: 606442; MGI: 106913; HomoloGene: 4209; GeneCards: ABI2; OMA:ABI2 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	203,447,728 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	60,520,317 bp
RNA expression pattern
	Top expressed in
	Brodmann area 23; ; entorhinal cortex; ; middle temporal gyrus; ; postcentral gyrus; ; external globus pallidus; ; internal globus pallidus; ; superior frontal gyrus; ; superior vestibular nucleus; ; ventral tegmental area; ; lateral nuclear group of thalamus;
	Top expressed in
	lateral septal nucleus; ; olfactory tubercle; ; anterior amygdaloid area; ; primary motor cortex; ; ventromedial nucleus; ; piriform cortex; ; Region I of hippocampus proper; ; cingulate gyrus; ; subiculum; ; nucleus accumbens;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; SH3 domain binding; kinase binding; protein binding; cytoskeletal anchor activity; proline-rich region binding; ubiquitin protein ligase binding; protein-containing complex binding; protein tyrosine kinase activator activity;
Cellular component	cytoplasm; cytosol; cell projection; SCAR complex; cytoskeleton; lamellipodium; filopodium; filopodium tip; dendrite; nucleus; adherens junction; cell junction; dendritic spine;
Biological process	positive regulation of Arp2/3 complex-mediated actin nucleation; cytoskeleton organization; peptidyl-tyrosine phosphorylation; Rac protein signal transduction; viral process; cell migration; actin polymerization or depolymerization; learning or memory; dendrite development; camera-type eye development; nervous system development; regulation of dendritic spine morphogenesis; lens fiber cell morphogenesis;
	Sources:Amigo / QuickGO
Orthologs
	10152
	329165
	ENSG00000138443
	ENSMUSG00000026782
	Q9NYB9
	P62484
	NM_001282925; NM_001282926; NM_001282927; NM_001282932; NM_005759
	NM_001198570; NM_001198571; NM_198127
NP_001269854; NP_001269855; NP_001269856; NP_001269861; NP_005750;
	NP_001362591; NP_001362592; NP_001362593; NP_001362594; NP_001362595; NP_001362596; NP_001362597; NP_001362598; NP_001362599; NP_001362600; NP_001362601; NP_001362602; NP_001362603; NP_001362604; NP_001362605; NP_001362606; NP_001362607; NP_001362608; NP_001362609; NP_001362610; NP_001362611; NP_001362612; NP_001362613; NP_001362614; NP_001362615; NP_001362616; NP_001362617; NP_001362618; NP_001362619; NP_001362620; NP_001362621; NP_001362622; NP_001362624; NP_001362625; NP_001362627; NP_001362628; NP_001362631; NP_001362633; NP_001362635; NP_001362636; NP_001362637; NP_001362638; NP_001362639; NP_001362640; NP_001362641; NP_001362643; NP_001362646; NP_001362648; NP_001362650; NP_001362651; NP_001362652; NP_001362653; NP_001362654; NP_001362655; NP_001362656; NP_001362657; NP_001362658; NP_001362659; NP_001362660; NP_001362661; NP_001362662; NP_001362663; NP_001362664; NP_001362665; NP_001362666; NP_001362667; NP_001362668; NP_001362669; NP_001362670; NP_001362671; NP_001362672; NP_001362673; NP_001362674; NP_001362675; NP_001362676; NP_001362677; NP_001362678; NP_001362679; NP_001362680; NP_001362681; NP_001362682; NP_001362683; NP_001362684
NP_001185499; NP_001185500; NP_937760; NP_001391634; NP_001391635;
	NP_001391636; NP_001391637; NP_001391638; NP_001391639; NP_001391640; NP_001391641; NP_001391642; NP_001391643; NP_001391644; NP_001391645; NP_001391646; NP_001391647; NP_001391648; NP_001391649; NP_001391650
	Wikidata
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Abl interactor 2 also known as Abelson interactor 2 (Abi-2) is a protein that in humans is encoded by the ABI2 gene.