5-IAI
| Clinical data | |
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| Other names | 5-Iodo-2-aminoindane; 5-Iodo-2-aminoindan; 5-IAI; NRG-5 |
| Routes of administration | Oral |
| Drug class | Serotonin–norepinephrine–dopamine releasing agent; Entactogen |
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| Pharmacokinetic data | |
| Duration of action | 2–4 hours |
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| Chemical and physical data | |
| Formula | C9H10IN |
| Molar mass | 259.090 g·mol−1 |
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| (what is this?) (verify) | |
5-Iodo-2-aminoindane (5-IAI) is an entactogen drug of the 2-aminoindane family. Human anecdotal reports suggest that it is entactogenic but produces little euphoria or stimulation.
The drug acts as a releasing agent of serotonin, norepinephrine, and dopamine. It produces much less serotonergic neurotoxicity than MDMA in animals.
5-IAI was developed in the 1990s by a team led by David E. Nichols at Purdue University. It was encountered as a novel recreational designer drug in 2010, but never gained widespread popularity.