3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase

3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase
Identifiers
EC no.2.1.1.116
CAS no.132084-81-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase (EC 2.1.1.116) is an enzyme that catalyzes the chemical reaction

(S)-3'-hydroxy-N-methylcoclaurine
+ SAM
 
 
 
 
 
 
 
+ SAH
 

The two substrates of this enzyme are (S)-3'-hydroxy-N-methylcoclaurine and S-adenosyl methionine (SAM). Its products are (S)-reticuline and S-adenosylhomocysteine (SAH).

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase. This enzyme participates in alkaloid biosynthesis.