2C-TFM

2C-TFM
Clinical data
Other names	2C-CF3; 2,5-Dimethoxy-4-trifluoromethylphenethylamine; 4-Trifluoromethyl-2,5-dimethoxyphenethylamine
Routes of; administration	Oral
Drug class	Serotonin 5-HT2 receptor agonist; Serotonergic psychedelic; Hallucinogen
Pharmacokinetic data
Duration of action	≥5–10 hours
Identifiers
	IUPAC name 2-[2,5-dimethoxy-4-(trifluoromethyl)phenyl]ethan-1-amine;
CAS Number	159277-08-4 ;
PubChem CID	10399795;
ChemSpider	8575233 ;
UNII	16O4G6IKYL;
ChEMBL	ChEMBL136354 ;
CompTox Dashboard (EPA)	DTXSID70439308 ;
Chemical and physical data
Formula	C11H14F3NO2
Molar mass	249.233 g·mol−1
3D model (JSmol)	Interactive image;
Melting point	260 °C (500 °F) (hydrochloride)
	SMILES FC(F)(C1=C(OC)C=C(CCN)C(OC)=C1)F;
	InChI InChI=1S/C11H14F3NO2/c1-16-9-6-8(11(12,13)14)10(17-2)5-7(9)3-4-15/h5-6H,3-4,15H2,1-2H3 ; Key:LYXGNMLWYONZID-UHFFFAOYSA-N ;
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2C-TFM, also known as 4-trifluoromethyl-2,5-dimethoxyphenethylamine or as 2C-CF₃, is a serotonin 5-HT₂ receptor agonist and psychedelic drug of the phenethylamine and 2C families. It was first synthesized in the laboratory of David E. Nichols. Later, it was tested in humans and its psychedelic effects were confirmed. 2C-TFM is the most potent psychedelic of the 2C psychedelics.