2C-T

2C-T
Clinical data
Other names	2C-T-1; 4-Methylthio-2,5-dimethoxyphenethylamine; 2,5-Dimethoxy-4-methylthiophenethylamine
Routes of; administration	Oral
Drug class	Serotonin 5-HT2 receptor agonist; Serotonin 5-HT2A receptor agonist; Serotonergic psychedelic; Hallucinogen
ATC code	None;
Legal status
Legal status	In general unscheduled;
Pharmacokinetic data
Onset of action	15 minutes
Duration of action	3–5 hours
Identifiers
	IUPAC name 2-[2,5-dimethoxy-4-(methylsulfanyl)phenyl]ethan-1-amine;
CAS Number	61638-09-3 ;
PubChem CID	12315927;
ChemSpider	10438674 ;
UNII	E5X0VFF7S4;
ChEMBL	ChEMBL127252 ;
CompTox Dashboard (EPA)	DTXSID60487530 ;
ECHA InfoCard	100.215.648
Chemical and physical data
Formula	C11H17NO2S
Molar mass	227.32 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES COC1=CC(=C(C=C1CCN)OC)SC;
	InChI InChI=1S/C11H17NO2S/c1-13-9-7-11(15-3)10(14-2)6-8(9)4-5-12/h6-7H,4-5,12H2,1-3H3 ; Key:UPZMYCMLLQTYEM-UHFFFAOYSA-N ;
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2C-T, or 2C-T-1, also known as 4-methylthio-2,5-dimethoxyphenethylamine, is a psychedelic drug of the phenethylamine and 2C families. It is taken orally. The drug has a relatively short duration and is of relatively low potency among the 2C psychedelics.

The drug acts as an agonist of the serotonin 5-HT₂ receptors, including of the serotonin 5-HT_2A receptor. It is the parent compound of the 2C-T series of psychedelic phenethylamines, with derivatives such as 2C-T-2, 2C-T-4, 2C-T-7, and 2C-T-21, among many others.

2C-T was first described in the scientific literature by David E. Nichols and Alexander Shulgin in 1976. It was described in greater detail by Shulgin in his 1991 book PiHKAL (Phenethylamines I Have Known and Loved). The drug was encountered as a novel designer drug in Europe in 2023.