2C-E

2C-E
Clinical data
Other names4-Ethyl-2,5-dimethoxyphenethylamine; 2,5-Dimethoxy-4-ethylphenethylamine; 2C-DOET; 2C-DOEt; Aquarust
Routes of
administration
Oral
Drug classSerotonin 5-HT2 receptor agonist; Serotonin 5-HT2A receptor agonist; Serotonergic psychedelic; Hallucinogen
ATC code
  • None
Legal status
Legal status
Pharmacokinetic data
Onset of action<2 hours
Duration of action8–12 hours
Identifiers
  • 2-(4-ethyl-2,5-dimethoxyphenyl)ethan-1-amine
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.221.016
Chemical and physical data
FormulaC12H19NO2
Molar mass209.289 g·mol−1
3D model (JSmol)
Solubility in water>70 mg/mL (20 °C)
  • COc1cc(CC)c(cc1CCN)OC
  • InChI=1S/C12H19NO2/c1-4-9-7-12(15-3)10(5-6-13)8-11(9)14-2/h7-8H,4-6,13H2,1-3H3 Y
  • Key:VDRGNAMREYBIHA-UHFFFAOYSA-N Y
  (verify)

2C-E, also known as 4-ethyl-2,5-dimethoxyphenethylamine, is a psychedelic drug of the phenethylamine and 2C families. It is taken orally.

2C-E was first synthesized by Alexander Shulgin in 1977 and was documented in his 1991 book PiHKAL (Phenethylamines I Have Known and Loved).