2025 US Open – Mixed doubles
| Mixed doubles | |
|---|---|
| 2025 US Open | |
| Champions | Sara Errani Andrea Vavassori |
| Runners-up | Iga Świątek Casper Ruud |
| Score | 6–3, 5–7, [10–6] |
| Draw | 16 |
| Seeds | 4 |
Sara Errani and Andrea Vavassori successfully defended their title, defeating Iga Świątek and Casper Ruud in the final, 6–3, 5–7, [10–6] to win the mixed doubles title at the 2025 US Open.
The 2025 US Open mixed doubles was part of the 2025 US Open, and was held on outdoor hard courts on August 19–20 at the USTA Billie Jean King National Tennis Center in New York City. It was the 137th time a mixed doubles competition was contested at the US Open.