2025 US Open – Girls' singles
| Girls' singles | |
|---|---|
| 2025 US Open | |
| Champion | Jeline Vandromme |
| Runner-up | Lea Nilsson |
| Score | 7–6(7–2), 6–2 |
| Draw | 16 |
| Seeds | 64 |
Jeline Vandromme won the girls' singles title at the 2025 US Open, defeating Lea Nilsson in the final, 7–6(7–2), 6–2. She did not lose a set en route to the title.
Mika Stojsavljevic was the defending champion, but lost in the semifinals to Nilsson.