2025 Rolex Shanghai Masters – Singles

Qualifier Valentin Vacherot defeated his first cousin Arthur Rinderknech in the final, 4–6, 6–3, 6–3 to win the singles tennis title at the 2025 Shanghai Masters. It was his first career ATP Tour title, and he defeated five seeded opponents consecutively en route. Vacherot was the first Monégasque player to win a tour singles title, the first unseeded champion at the Shanghai Masters, and the lowest-ranked ATP Masters 1000 champion (ranked No. 204). Vacherot was the third qualifier (after Roberto Carretero and Albert Portas at the 1996 and 2001 Hamburg Masters, respectively) to win a Masters 1000 title, and the fifth player overall to win a Masters 1000 as their first tour-level title.

For the first time in the tournament's history, two unseeded players contested the final, and this was only the third all-unseeded Masters 1000 final (after the 1996 Hamburg Masters and the 2003 Paris Masters). Vacherot and Rinderknech are cousins, and were the first pair of family members to contest an ATP Tour final since brothers John and Patrick McEnroe at the 1991 Chicago Open.

At 38 years, 140 days old, Novak Djokovic reached a record 80th Masters semifinal and extended his record as the oldest semifinalist (since the format's establishment in 1990). The second-round match between Djokovic (38 years, 134 days) and Marin Čilić (37 years, 5 days) was the oldest ATP 1000 singles match in terms of combined ages (75 years and 139 days) (since 1990).

Jannik Sinner was the defending champion, but retired in the third round against Tallon Griekspoor.