2025 Hall of Fame Open – Women's singles

Women's singles
2025 Hall of Fame Open
Champion Caty McNally
Runner-up Tatjana Maria
Score2–6, 6–4, 6–2

This was the first edition of the women's event at the Hall of Fame Open and the first women's tennis tournament to be held at the International Tennis Hall of Fame since the defunct Virginia Slims of Newport tournament, last held as a competitive event in 1990.

Caty McNally won the women's singles title, defeating Tatjana Maria in the final, 2–6, 6–4, 6–2.