2025 Cure Bowl
| 2025 StaffDNA Cure Bowl | |||||||||||||||||||
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| 11th Cure Bowl | |||||||||||||||||||
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| Date | December 17, 2025 | ||||||||||||||||||
| Season | 2025 | ||||||||||||||||||
| Stadium | Camping World Stadium | ||||||||||||||||||
| Location | Orlando, Florida | ||||||||||||||||||
| MVP | Quinn Henicle (QB, Old Dominion) | ||||||||||||||||||
| Favorite | South Florida by 2.5 | ||||||||||||||||||
| Referee | Ron Hudson (Conference USA) | ||||||||||||||||||
| Attendance | 15,036 | ||||||||||||||||||
| United States TV coverage | |||||||||||||||||||
| Network | ESPN | ||||||||||||||||||
| Announcers | Dave Neal (play-by-play), Fozzy Whittaker (analyst), and Morgan Uber (sideline reporter) Jamie Seh (play-by-play) and Rene Ingoglia (analyst) (Bowl Season Radio) | ||||||||||||||||||
The 2025 Cure Bowl was a college football bowl game played on December 17, 2025, at Camping World Stadium located in Orlando, Florida. The eleventh annual Cure Bowl featured the South Florida Bulls from the American Conference and the Old Dominion Monarchs from the Sun Belt Conference. The game began at approximately 5:00 p.m. EST and aired on ESPN. The Cure Bowl was one of the 2025–26 bowl games concluding the 2025 FBS football season. The game was sponsored by StaffDNA, a digital marketplace for healthcare jobs, and was officially known as the StaffDNA Cure Bowl.
The 2025 Cure Bowl featured the Old Dominion Monarchs (9–3) of the Sun Belt Conference and the South Florida Bulls (9–3) of the American Conference. Old Dominion beat South Florida by a score of 24–10.