2025 Cincinnati Open – Men's singles

Men's singles
2025 Cincinnati Open
Champion Carlos Alcaraz
Runner-up Jannik Sinner
Score5–0 ret.
Draw96
Seeds32

Carlos Alcaraz won the men's singles tennis title at the 2025 Cincinnati Open after defending champion Jannik Sinner retired in the final, with the score at 5–0. It was his eighth Masters 1000 title and 22nd ATP Tour title overall. Alcaraz was the youngest man to win Cincinnati since Andy Murray in 2008. This was the first time since 2011 that the final ended in a retirement.

Térence Atmane was the first qualifier to reach the tournament's semifinals since Alexandr Dolgopolov in 2015.