2022 ABN AMRO Rotterdam – Singles
| Singles | |
|---|---|
| 2022 ABN AMRO Rotterdam | |
| Champion | Félix Auger-Aliassime |
| Runner-up | Stefanos Tsitsipas |
| Score | 6–4, 6–2 |
| Draw | 32 (4 Q / 3 WC ) |
| Seeds | 8 |
Félix Auger-Aliassime defeated Stefanos Tsitsipas in the final, 6–4, 6–2 to win the singles tennis title at the 2022 Rotterdam Open. It was his first ATP Tour singles title, following eight runner-up finishes in prior finals.
Andrey Rublev was the defending champion, but lost in the semifinals to Auger-Aliassime. Rublev reached his 11th consecutive quarterfinal at an ATP 500 tournament.