2021 FBF División Profesional

División Profesional
Season2021
Dates9 March – 12 December 2021
ChampionsIndependiente Petrolero (1st title)
RelegatedReal Potosí
San José
Copa LibertadoresIndependiente Petrolero
Always Ready
The Strongest
Bolívar
Copa SudamericanaRoyal Pari
Oriente Petrolero
Jorge Wilstermann
Guabirá
Matches239
Goals734 (3.07 per match)
Top goalscorerMartín Prost (18 goals)
Biggest home winThe Strongest 7–0 Nacional Potosí
(18 August)
Biggest away winAurora 0–8 Royal Pari
(11 March)
Highest scoringIndep. Petrolero 5–4 Wilstermann
(25 April)
2020
2022

The 2021 FBF División Profesional, known as the 2021 Copa Tigo for sponsorship reasons, was the 44th season of the División Profesional del Fútbol Boliviano, Bolivia's top-flight football league and the fourth season under División de Fútbol Profesional management. The season began on 9 March and ended on 12 December 2021.

Independiente Petrolero won their first league title following a 3–2 win over Guabirá and a 1–0 loss for The Strongest against Real Santa Cruz on the last day of the season. Always Ready were the defending champions, having won the 2020 Apertura tournament.