2021–22 Louisville Cardinals women's basketball team

2021–22 Louisville Cardinals women's basketball
NCAA tournament, Final Four
ConferenceAtlantic Coast Conference
Ranking
CoachesNo. 4
APNo. 4
Record29–5 (16–2 ACC)
Head coach
Assistant coaches
Home arenaKFC Yum! Center
2021–22 ACC women's basketball standings
Conf. Overall
Team W   L   PCT W   L   PCT
No. 3 NC State 17 1   .944 32 4   .889
No. 4 Louisville 16 2   .889 29 5   .853
No. 17 North Carolina 13 5   .722 25 7   .781
No. 21 Notre Dame 13 5   .722 24 9   .727
No. 16 Virginia Tech 13 5   .722 23 10   .697
Georgia Tech 11 7   .611 21 11   .656
Boston College 10 8   .556 21 12   .636
Miami (FL) 10 8   .556 21 13   .618
Florida State 10 8   .556 17 14   .548
Duke 7 11   .389 17 13   .567
Wake Forest 4 14   .222 16 17   .485
Syracuse 4 14   .222 11 18   .379
Clemson 3 15   .167 10 21   .323
Pittsburgh 2 16   .111 11 19   .367
Virginia 2 16   .111 5 22   .185
2022 ACC tournament winner
Rankings from AP poll

The 2021–22 Louisville Cardinals women's basketball team represented the University of Louisville during the 2021–22 NCAA Division I women's basketball season. The Cardinals, were led by 15th-year head coach Jeff Walz, and played their home games at the KFC Yum! Center in their eight year in the Atlantic Coast Conference.

They finished the season 29–5 overall and 16–2 in ACC play to finish in second place. As the second seed in the ACC tournament, they were upset by seventh seed Miami in the Quarterfinals. They received and at-large bid to the NCAA tournament and were the first seed in the Wichita Regional. They defeated sixteenth seed Albany in the First Round, ninth seed Gonzaga in the Second Round, fourth seed Tennessee in the Sweet Sixteen, and third seed Michigan in the Elite Eight before falling to eventual champions, and first seed South Carolina in the Final Four. This was the Cardinals fourth appearance in the Final Four in program history.