2011 Western & Southern Open – Men's singles

Men's singles
2011 Western & Southern Open
Champion Andy Murray
Runner-up Novak Djokovic
Score6–4, 3–0 ret.

Andy Murray won the men's singles title at the 2011 Cincinnati Masters after Novak Djokovic retired from the final, with the scoreline at 6–4, 3–0. It was Murray's seventh Masters title. Djokovic's retirement in the final marked only his second defeat of the season.

Roger Federer was the two-time defending champion, but lost to Tomáš Berdych in the quarterfinals.