2008 Italian Open – Men's singles

Men's singles
2008 Italian Open
Champion Novak Djokovic
Runner-up Stanislas Wawrinka
Score4–6, 6–3, 6–3
Draw56 (4WC/7Q)
Seeds16
Main article: 2008 Italian Open (tennis)

Novak Djokovic defeated Stanislas Wawrinka in the final, 4–6, 6–3, 6–3 to win the men's singles tennis title at the 2008 Italian Open.

Rafael Nadal was the three-time defending champion, but lost in the second round to Juan Carlos Ferrero. Notably, this marked the first of two instances that Nadal lost his opening match at a clay court tournament.

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