2001 Cheltenham & Gloucester Trophy
| Administrator | England and Wales Cricket Board |
|---|---|
| Cricket format | Limited overs cricket(50 overs per innings) |
| Tournament format | Knockout |
| Champions | Somerset (3rd title) |
| Participants | 56 |
| Matches | 55 |
| Most runs | 258 Graeme Hick (Worcestershire) |
| Most wickets | 10 Peter Martin (Lancashire) |
The 2001 Cheltenham and Gloucester Trophy was an English limited overs county cricket tournament which was held between 1 May and 1 September 2001. It was the first Cheltenham & Gloucester Trophy following its change of name from the NatWest Trophy, with new sponsors Cheltenham & Gloucester plc. The tournament was won by Somerset who defeated Leicestershire by 41 runs in the final at Lord's.