2-Hydroxyisocaproic acid

2-Hydroxyisocaproic acid
Names
Preferred IUPAC name
2-Hydroxy-4-methylpentanoic acid
Other names
2-Hydroxy-4-methylvaleric acid
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.007.147
UNII
  • InChI=1S/C6H12O3/c1-4(2)3-5(7)6(8)9/h4-5,7H,3H2,1-2H3,(H,8,9)
    Key: LVRFTAZAXQPQHI-UHFFFAOYSA-N
  • InChI=1/C6H12O3/c1-4(2)3-5(7)6(8)9/h4-5,7H,3H2,1-2H3,(H,8,9)
    Key: LVRFTAZAXQPQHI-UHFFFAOYAQ
  • CC(C)CC(C(=O)O)O
Properties
C6H12O3
Molar mass 132.159 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

2-Hydroxyisocaproic acid (HICA or leucic acid) is a metabolite of the branched-chain amino acid leucine. It is commonly sold as a purported muscle building supplement. It also has fungicidal properties. HICA was shown to increase protein synthesis and muscle mass in rats who were recovering from a period of induced atrophy.

HICA is also produced by several protozoans it has been reported to show anti- inflammatory activities.

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