2-Aminofluorene
Structure of 2-aminofluorene
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| Names | |
|---|---|
| Systematic IUPAC name
9H-Fluoren-2-amine | |
| Other names
2-Fluorenamine; 2-fluoreneamine
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| Identifiers | |
3D model (JSmol)
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| Abbreviations | 2-AF |
| ChEMBL | |
| ChemSpider | |
| ECHA InfoCard | 100.005.290 |
| EC Number |
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PubChem CID
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| UNII | |
| UN number | 2811 |
CompTox Dashboard (EPA)
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| Properties | |
| C13H11N | |
| Molar mass | 181.238 g·mol−1 |
| Appearance | White to tan solid |
| Melting point | 125–132 °C (257–270 °F; 398–405 K) |
| <.1 g/100 mL at 19.5 °C | |
| Hazards | |
| Occupational safety and health (OHS/OSH): | |
Main hazards
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Cytotoxic |
| GHS labelling: | |
| Warning | |
| H341, H351 | |
| P201, P280, P308+P313 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
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2-Aminofluorene (2-AF) is a synthetic arylamine. It is a white to tan solid with a melting point of 125-132 °C. 2-AF has only been tested in controlled laboratory settings thus far. There is no indication that it will be tested in industrialized settings. There is evidence that 2-aminofluorene is a carcinogen and an intercalating agent that is extremely dangerous to genomic DNA that potentially can lead to mutation if not death. Furthermore, it has been suggested that 2-aminofluorene can undergo acetylation reactions that causes these reactive species to undergo such reactions in cells. Several experiments have been conducted that have suggested 2-aminofluorene be treated with care and with an overall awareness of the toxicity of this compound.