1999 US Open – Men's singles
| Men's singles | |
|---|---|
| 1999 US Open | |
| Champion | Andre Agassi |
| Runner-up | Todd Martin |
| Score | 6–4, 6–7(5–7), 6–7(2–7), 6–3, 6–2 |
| Draw | 128 |
| Seeds | 16 |
Andre Agassi defeated Todd Martin in the final, 6–4, 6–7(5–7), 6–7(2–7), 6–3, 6–2 to win the men's singles tennis title at the 1999 US Open. It was his second US Open title and fifth major title overall. With the win, Agassi returned to the world No. 1 singles ranking, ultimately ending Pete Sampras' record streak of six year-end No. 1 rankings.
Pat Rafter was the two-time defending champion, but lost to Cédric Pioline in the first round after succumbing to shoulder tendinitis.
This tournament marked the first main-draw major appearance of future world No. 1 and 2003 French Open champion Juan Carlos Ferrero; he lost to Greg Rusedski in the first round.