1980–81 Louisville Cardinals men's basketball team

1980–81 Louisville Cardinals men's basketball
Metro Conference Champions
Metro Conference tournament champions
ConferenceMetro Conference
Ranking
CoachesNo. 13
APNo. 12
Record21–9 (11–1 Metro)
Head coach
CaptainGame captains
Home arenaFreedom Hall
1980–81 Metro Conference men's basketball standings
Conf. Overall
Team W   L   PCT W   L   PCT
No. 12 Louisville 11 1   .917 21 9   .700
Florida State 7 5   .583 17 11   .607
Cincinnati 6 6   .500 16 13   .552
Virginia Tech 6 6   .500 15 13   .536
Memphis State 5 7   .417 13 14   .481
Tulane 4 8   .333 12 15   .444
Saint Louis 3 9   .250 9 18   .333
1981 Metro Conference tournament winner
Rankings from AP Poll

The 1980–81 Louisville Cardinals men's basketball team represented the University of Louisville during the 1980-81 NCAA Division I men's basketball season, Louisville's 67th season of intercollegiate competition. The Cardinals competed in the Metro Conference and were coached by Denny Crum, who was in his tenth season. The team played its home games at Freedom Hall.

The Cardinals won the Metro Conference tournament championship (their 3rd), defeating Cincinnati 42–31. As defending Champion Louisville was upset by a half-court shot by U.S. Reed and lost to Arkansas 74–73 in the NCAA tournament second round. The Cardinals finished with a 21–9 (11–1) record.