1941 Campeonato Nacional Primera División
| Dates | 30 May 1941 – 8 November 1941 |
|---|---|
| Champions | Colo-Colo (3rd title) |
| Matches | 90 |
| Goals | 407 (4.52 per match) |
| Top goalscorer | José Profetta (19 goals) |
| Biggest home win | Audax Italiano 6–1 Universidad Católica (15 June) Universidad de Chile 6–1 Santiago National J. (27 July) |
| Total attendance | 320,029 |
| Average attendance | 3,636 |
← 1940 1942 → | |
The 1941 Campeonato Nacional de Fútbol Profesional was Chilean first tier’s 9th season. Colo-Colo was the tournament’s champion, winning its 3rd title.