1521–1522 conclave

Papal conclave
1521–22
Dates and location
28 December 1521 – 9 January 1522
Apostolic Palace, Papal States
Key officials
DeanBernardino de Sande
CamerlengoFrancesco de' Medici
ProtodeaconGiulio de' Medici
Election
Candidates
Elected pope
Adriaan Boeyens
Name taken: Adrian VI

The 1521–22 papal conclave elected Pope Adrian VI to succeed Pope Leo X. The conclave was marked by the early candidacies of cardinal-nephew Giulio de'Medici (future Pope Clement VII) and Alessandro Farnese (future Pope Paul III), although the Colonna and other cardinals blocked their election.

Adrian, the viceroy to Spain and a clear pro-Imperial candidate, was elected as a compromise candidate despite his absence from the conclave. The number of cardinal-electors (thirty-nine) and the length of the sede vacante increased the cost of the conclave even in excess of the funds distributed by Charles V, Holy Roman Emperor, Francis I of France, and Henry VIII of England to promote their candidates.