(S)-coclaurine-N-methyltransferase

(S)-coclaurine-N-methyltransferase
Identifiers
EC no.2.1.1.140
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, (S)-coclaurine-N-methyltransferase (EC 2.1.1.140) is an enzyme that catalyzes the chemical reaction

+ SAM
 
 
 
 
 
 
 
(S)-N-methylcoclaurine
+ SAH
 

S-adenosyl methionine (SAM) provides the methyl group for alkylation of (S)-coclaurine, which is converted to (S)-N-methylcoclaurine, with S-adenosylhomocysteine (SAH) as a by-product.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:(S)-coclaurine-N-methyltransferase. This enzyme participates in alkaloid biosynthesis.