(+)-CPCA

(+)-CPCA
Clinical data
ATC code
  • none
Identifiers
  • Methyl (3R,4S)-4-(4-chlorophenyl)-1-methylpiperidine-3-carboxylate
CAS Number
PubChem CID
ChemSpider
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC14H18ClNO2
Molar mass267.75 g·mol−1
3D model (JSmol)
  • Clc1ccc(cc1)[C@@H]2[C@@H](C(=O)OC)CN(C)CC2
  • InChI=1S/C14H18ClNO2/c1-16-8-7-12(13(9-16)14(17)18-2)10-3-5-11(15)6-4-10/h3-6,12-13H,7-9H2,1-2H3/t12-,13+/m1/s1 N
  • Key:GDFVYUDIAQQDTA-OLZOCXBDSA-N N
 NY (what is this?)  (verify)

(+)-CPCA (nocaine, 3α-carbomethoxy-4β-(4-chlorophenyl)-N-methylpiperidine aka CTDP 31,446) is a stimulant drug similar in structure to pethidine (an opioid that possesses NDRI actions) and to RTI-31, but nocaine lacks the two-carbon bridge of RTI-31's tropane skeleton. This compound was first developed as a substitute agent for cocaine.

The nocaine family includes a diverse assortment of piperidine based cocaine mimetics. The parent compound nocaine was developed in an attempt to create a substitute drug for cocaine for the treatment of addiction, and was found to substitute for cocaine in animal models while having significantly less abuse potential.