Delta endotoxins

Delta endotoxin, N-terminal domain
crystal structure of the insecticidal bacterial del endotoxin Cry3Bb1 Bacillus thuringiensis
Identifiers
SymbolEndotoxin_N
PfamPF03945
InterProIPR005639
SCOP21dlc / SCOPe / SUPFAM
TCDB1.C.2
Available protein structures:
PDB  IPR005639 PF03945 (ECOD; PDBsum)  
AlphaFold
Delta endotoxin, middle domain
Identifiers
SymbolEndotoxin_M
PfamPF00555
Pfam clanCL0568
InterProIPR015790
SCOP21dlc / SCOPe / SUPFAM
TCDB1.C.2
Available protein structures:
PDB  IPR015790 PF00555 (ECOD; PDBsum)  
AlphaFold
Delta endotoxin, C-terminal
Identifiers
SymbolEndotoxin_C
PfamPF03944
Pfam clanCL0202
InterProIPR005638
SCOP21dlc / SCOPe / SUPFAM
TCDB1.C.2
CDDcd04085
Available protein structures:
PDB  IPR005638 PF03944 (ECOD; PDBsum)  
AlphaFold
Cytolytic delta-endotoxin Cyt1/2
Identifiers
SymbolCytB
PfamPF01338
InterProIPR001615
SCOP21cby / SCOPe / SUPFAM
TCDB1.C.71
Available protein structures:
PDB  IPR001615 PF01338 (ECOD; PDBsum)  
AlphaFold

Delta endotoxins (δ-endotoxins) are a family of pore-forming toxins produced by Bacillus thuringiensis species of bacteria. They are useful for their insecticidal action and are the primary toxin produced by the genetically modified (GM) Bt maize/corn and other GM crops. During spore formation the bacteria produce crystals of such proteins (hence the name Cry toxins) that are also known as parasporal bodies, next to the endospores; as a result some members are known as a parasporin. The Cyt (cytolytic) toxin group is another group of delta-endotoxins formed in the cytoplasm. VIP toxins (vegetative insecticidal proteins) are formed at other stages of the life cycle.

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