α-Ethyl-N-methylphenethylamine

MEPEA
Clinical data
Other names	N-Methyl-α-ethylphenethylamine; MEPEA; α-Et-N-Me-PEA; α-Et-MPEA; α-Et-NM-PEA; α-Et-Meth; α-Ethyl-methamphetamine; AENMPEA; AEMPEA; 2-Methylamino-1-phenylbutane; N-Methyl-1-phenyl-2-butanamine; PAL-426; PAL426
Drug class	Norepinephrine–dopamine releasing agent; Stimulant; Sympathomimetic
Identifiers
	IUPAC name N-methyl-1-phenylbutan-2-amine;
CAS Number	84952-60-3;
PubChem CID	551747;
ChemSpider	479992;
UNII	GTM6NOX2CN;
ChEBI	CHEBI:183993;
ChEMBL	ChEMBL3305872;
CompTox Dashboard (EPA)	DTXSID40874247 ;
Chemical and physical data
Formula	C11H17N
Molar mass	163.264 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCC(CC1=CC=CC=C1)NC;
	InChI InChI=1S/C11H17N/c1-3-11(12-2)9-10-7-5-4-6-8-10/h4-8,11-12H,3,9H2,1-2H3; Key:ONNVUALDGIKEIJ-UHFFFAOYSA-N;

α-Ethyl-N-methylphenethylamine (MEPEA; code name PAL-426) is a stimulant, designer drug, and norepinephrine–dopamine releasing agent (NDRA) of the phenethylamine, amphetamine, and phenylisobutylamine (α-ethylphenethylamine) families. It is the N-methyl derivative of phenylisobutylamine (α-ethylphenethylamine; AEPEA) and is the α-ethyl homologue of methamphetamine (α-methyl-N-methylphenethylamine).

The drug's EC₅₀Tooltip half-maximal effective concentration values for induction of monoamine release are 58 nM for norepinephrine, 179 to 225 nM for dopamine, and 4,698 nM for serotonin. Like amphetamine, MEPEA produces hyperlocomotion and sympathomimetic effects in rodents. It is about one-tenth as potent as d-methamphetamine in drug discrimination and other tests in rodents.

MEPEA was first described in the scientific literature by 1984. It has been encountered as an ingredient in dietary supplements.